Bariatric Surgery
Published
August 8, 2026
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3400
SADI-S Surgery Explained: What Patients Need to Know
SADI‑S combines a sleeve gastrectomy with a single intestinal bypass to deliver DS‑level metabolic power with lower surgical complexity. Learn how it works, who it’s for, and what to expect long‑term.

Quick Answer
SADI‑S begins with a sleeve and adds a single duodeno‑ileal connection. It produces 30–45% total body weight loss, strong diabetes remission, and durable metabolic improvement with fewer anastomoses than DS.
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Article
Published Date:
2026-09-12 21:33
Word Count:
3400
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14
Obesity By The Numbers
Key statistics that highlight the growing impact of obesity.
SADI‑S increases GLP‑1, reduces insulin resistance, accelerates nutrient delivery to the ileum, and produces the strongest metabolic effect short of full DS.
Medical Topics Covered
This article covers the following medical topics and related areas.


Nestor de la Cruz-Muñoz, MD, FACS, DABOM
About the Author
Nestor de la Cruz‑Muñoz, MD, FACS, DABOM
Dr. Nestor de la Cruz‑Muñoz is a nationally recognized bariatric, metabolic, and foregut surgeon with more than 20 years of experience treating complex obesity‑related and gastrointestinal conditions. He serves as the Medical Director of Bariatric and Metabolic Surgery at HCA Florida Mercy Hospital and has held academic appointments as a Professor of Surgery at a major university‑based medical center.
Dr. de la Cruz‑Muñoz specializes in advanced minimally invasive and robotic surgery, metabolic disease management, and comprehensive long‑term patient care. His work integrates clinical expertise, academic leadership, and a commitment to evidence‑based medicine. He has trained surgeons across the country, contributed to national guidelines, and is widely regarded for his outcomes, innovation, and patient‑centered approach.
Patients choose Dr. de la Cruz‑Muñoz for his combination of surgical excellence, metabolic expertise, and lifelong dedication to improving patient health through compassionate, high‑quality care.
Dr. de la Cruz‑Muñoz specializes in advanced minimally invasive and robotic surgery, metabolic disease management, and comprehensive long‑term patient care. His work integrates clinical expertise, academic leadership, and a commitment to evidence‑based medicine. He has trained surgeons across the country, contributed to national guidelines, and is widely regarded for his outcomes, innovation, and patient‑centered approach.
Patients choose Dr. de la Cruz‑Muñoz for his combination of surgical excellence, metabolic expertise, and lifelong dedication to improving patient health through compassionate, high‑quality care.













